Yes. Copy the desktop WooPOS icon, right-click to change properties.

Add this at end of target line:

Instance WooPOSCosmeticLabs 1799


Instance WooPOS2 1799

In this case, CosmeticLabs is the business name, 1799 is SQL TCP/IP port.

Double click this icon on the desktop, follow WooPOS setup wizard to start the second business setup. Please use a different Email account in the setup.